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Wealthy nations difference between proair hfa and ventolin hfa must do much more, much faster.The United Nations General Assembly in get ventolin prescription online September 2021 will bring countries together at a critical time for marshalling collective action to tackle the global environmental crisis. They will meet again at the biodiversity summit in Kunming, China, and the climate conference (Conference of the Parties (COP)26) in Glasgow, UK. Ahead of these pivotal meetings, we—the editors of health journals worldwide—call for urgent action to keep average global temperature increases below 1.5°C, halt the destruction of nature and protect health.Health is already being harmed by global temperature get ventolin prescription online increases and the destruction of the natural world, a state of affairs health professionals have been bringing attention to for decades.1 The science is unequivocal. A global increase of 1.5°C above the preindustrial average and the continued loss of biodiversity risk catastrophic harm to health that will be impossible to reverse.2 3 Despite the world’s necessary preoccupation with asthma treatment, we cannot wait for the ventolin to pass to rapidly reduce emissions.Reflecting the severity of the moment, this editorial appears in health journals across the world. We are united get ventolin prescription online in recognising that only fundamental and equitable changes to societies will reverse our current trajectory.The risks to health of increases above 1.5°C are now well established.2 Indeed, no temperature rise is ‘safe’.

In the past 20 years, heat-related mortality among people aged over 65 has increased by more than 50%.4 Higher temperatures have brought increased dehydration and renal function loss, dermatological malignancies, tropical s, adverse mental health outcomes, pregnancy complications, allergies, and cardiovascular and pulmonary morbidity and mortality.5 6 Harms disproportionately affect the most vulnerable, including children, older populations, ethnic minorities, poorer communities and those with underlying health problems.2 4Global heating is also contributing to the decline in global yield potential for major crops, falling by 1.8%–5.6% since 1981. This, together with the effects of extreme weather and soil depletion, is hampering efforts to reduce undernutrition.4 Thriving ecosystems are essential to human health, and the widespread destruction of nature, including habitats and species, is eroding water and food security and increasing the chance of ventolins.3 7 8The consequences of the environmental crisis fall disproportionately on those countries and communities that have contributed least to the problem and are least able to mitigate the harms. Yet no country, no matter how wealthy, can shield itself from these get ventolin prescription online impacts. Allowing the consequences to fall disproportionately on the most vulnerable will breed more conflict, food insecurity, forced displacement and zoonotic disease, with severe implications for all countries and communities. As with the asthma treatment ventolin, we are globally as strong as our weakest get ventolin prescription online member.Rises above 1.5°C increase the chance of reaching tipping points in natural systems that could lock the world into an acutely unstable state.

This would critically impair our ability to mitigate harms and to prevent catastrophic, runaway environmental change.9 10Global targets are not enoughEncouragingly, many governments, financial institutions and businesses are setting targets to reach net-zero emissions, including targets for 2030. The cost of renewable energy is dropping rapidly. Many countries are get ventolin prescription online aiming to protect at least 30% of the world’s land and oceans by 2030.11These promises are not enough. Targets are easy to set and hard to achieve. They are yet to be matched with credible short-term get ventolin prescription online and longer-term plans to accelerate cleaner technologies and transform societies.

Emissions reduction plans do not adequately incorporate health considerations.12 Concern is growing that temperature rises above 1.5°C are beginning to be seen as inevitable, or even acceptable, to powerful members of the global community.13 Relatedly, current strategies for reducing emissions to net zero by the middle of the century implausibly assume that the world will acquire great capabilities to remove greenhouse gases from the atmosphere.14 15This insufficient action means that temperature increases are likely to be well in excess of 2°C,16 a catastrophic outcome for health and environmental stability. Critically, the destruction of nature does not have parity of esteem with the climate element of the crisis, and every single global target to restore biodiversity loss by 2020 was missed.17 This is an overall environmental crisis.18Health professionals are united with environmental scientists, businesses and many others in rejecting that this outcome is inevitable. More can and must be done now—in Glasgow and Kunming—and in the immediate years that get ventolin prescription online follow. We join health professionals worldwide who have already supported calls for rapid action.1 19Equity must be at the centre of the global response. Contributing a fair share to the global effort means get ventolin prescription online that reduction commitments must account for the cumulative, historical contribution each country has made to emissions, as well as its current emissions and capacity to respond.

Wealthier countries will have to cut emissions more quickly, making reductions by 2030 beyond those currently proposed20 21 and reaching net-zero emissions before 2050. Similar targets and emergency action are needed for biodiversity loss and the wider destruction of the natural world.To achieve these targets, governments must make fundamental changes to how our societies and economies are organised and how we live. The current strategy get ventolin prescription online of encouraging markets to swap dirty for cleaner technologies is not enough. Governments must intervene to support the redesign of transport systems, cities, production and distribution of food, markets for financial investments, health systems, and much more. Global coordination is needed to ensure that get ventolin prescription online the rush for cleaner technologies does not come at the cost of more environmental destruction and human exploitation.Many governments met the threat of the asthma treatment ventolin with unprecedented funding.

The environmental crisis demands a similar emergency response. Huge investment will be needed, beyond what is being considered or delivered anywhere in the world. But such investments will produce huge positive health and economic outcomes get ventolin prescription online. These include high-quality jobs, reduced air pollution, increased physical activity, and improved housing and diet. Better air quality alone would realise get ventolin prescription online health benefits that easily offset the global costs of emissions reductions.22These measures will also improve the social and economic determinants of health, the poor state of which may have made populations more vulnerable to the asthma treatment ventolin.23 But the changes cannot be achieved through a return to damaging austerity policies or the continuation of the large inequalities of wealth and power within and between countries.Cooperation hinges on wealthy nations doing moreIn particular, countries that have disproportionately created the environmental crisis must do more to support low-income and middle-income countries to build cleaner, healthier and more resilient societies.

High-income countries must meet and go beyond their outstanding commitment to provide $100 billion a year, making up for any shortfall in 2020 and increasing contributions to and beyond 2025. Funding must be equally split between mitigation and adaptation, including improving the resilience of health systems.Financing should be through grants rather than loans, building local capabilities and truly empowering communities, and should come alongside forgiving large debts, which constrain the agency of so many low-income countries. Additional funding must be marshalled to compensate for inevitable get ventolin prescription online loss and damage caused by the consequences of the environmental crisis.As health professionals, we must do all we can to aid the transition to a sustainable, fairer, resilient and healthier world. Alongside acting to reduce the harm from the environmental crisis, we should proactively contribute to global prevention of further damage and action on the root causes of the crisis. We must hold global leaders to account and continue to educate others about the get ventolin prescription online health risks of the crisis.

We must join in the work to achieve environmentally sustainable health systems before 2040, recognising that this will mean changing clinical practice. Health institutions have already divested more than $42 billion of assets from fossil fuels. Others should join them.4The greatest threat to global public health is the continued failure of world leaders to keep the global get ventolin prescription online temperature rise below 1.5°C and to restore nature. Urgent, society-wide changes must be made and will lead to a fairer and healthier world. We, as editors of health journals, call for governments and other leaders get ventolin prescription online to act, marking 2021 as the year that the world finally changes course.Ethics statementsPatient consent for publicationNot required.IntroductionThe asthma treatment ventolin is expected to have far-reaching consequences on population health, particularly in already disadvantaged groups.1 2 Aside from direct effects of asthma treatment , detrimental changes may include effects on physical and mental health due to associated changes to health-impacting behaviours.

Change in such behaviours may be anticipated due to the effects of social distancing, both mandatory and voluntary, and change in factors which may affect such behaviours—such as employment, financial circumstances and mental distress.3 4 The behaviours investigated here include physical activity, diet, alcohol and sleep5—likely key contributors to existing health inequalities6 and indirectly implicated in inequalities arising due to asthma treatment given their link with outcomes such as obesity and diabetes.7While empirical evidence of the impact of asthma treatment on such behaviours is emerging,8–26 it is currently difficult to interpret for multiple reasons. First, generalising from one study location and/or period of data collection to another is complicated by the vastly different societal responses to asthma treatment which could plausibly impact on such behaviours, such as restrictions to movement, access to restaurants/pubs and access to support services to reduce substance use. This is get ventolin prescription online compounded by many studies investigating only one health behaviour in isolation. Further, assessment of change in any given outcome is notoriously methodologically challenging.27 Some studies have questionnaire instruments which appear to focus only on the negative consequences of asthma treatment,8 thus curtailing an assessment of both the possible positive and negative effects on health behaviours.The consequences of asthma treatment lockdown on behavioural outcomes may differ by factors such as age, gender, socioeconomic position (SEP) and ethnicity—thus potentially widening already existing health inequalities. For instance, younger get ventolin prescription online generations (eg, age 18–30 years) are particularly affected by cessation or disruption of education, loss of employment and income,3 and were already less likely than older persons to be in secure housing, secure employment or stable partnerships.28 In contrast, older generations appear more susceptible to severe consequences of asthma treatment , and in many countries were recommended to ‘shield’ to prevent such .

Within each generation, the ventolin’s effects may have had inequitable effects by gender (eg, childcare responsibilities being borne more by women), SEP and ethnicity (eg, more likely to be in at-risk and low paid employment, insecure and crowded housing).Using data from five nationally representative British cohort studies, which each used an identical asthma treatment follow-up questionnaire in May 2020, we investigated change in multiple health-impacting behaviours. Multiple outcomes were investigated since each is likely to have independent impacts on population health, and evidence-based policy decisions are likely better informed by simultaneous consideration of multiple outcomes.29 We considered multiple well-established health equity stratifiers30. Age/cohort, gender, socioeconomic position (SEP) get ventolin prescription online and ethnicity. Further, since childhood SEP may impact on adult behaviours and health outcomes independently of adult SEP,31 we used previously collected prospective data in these cohorts to investigate childhood and adult SEP.MethodsStudy samplesWe used data from four British birth cohort (c) studies, born in 1946,32 1958,33 197034 and 2000–2002 (born 2000–2002. 2001c, inclusive get ventolin prescription online of Northern Ireland)35.

And one English longitudinal cohort study (born 1989–90. 1990c) initiated from 14 years.36 Each has been followed up at regular intervals from birth or adolescence. On health, behavioural get ventolin prescription online and socioeconomic factors. In each study, participants gave written consent to be interviewed. In May 2020, during the asthma treatment ventolin, participants were invited to take part in an online questionnaire which measured demographic factors, health measures and multiple behaviours.37OutcomesWe investigated the get ventolin prescription online following behaviours.

Sleep (number of hours each night on average), exercise (number of days per week (ie, from 0 to 7) the participants exercised for 30 min or more at moderate-vigorous intensity—“working hard enough to raise your heart rate and break into a sweat”) and diet (number of portions of fruit and vegetables per day (from 0 to ≥6). Portion guidance was provided). Alcohol consumption was reported in both consumption frequency (never to 4 or more times per week) and the typical number of drinks consumed when drinking get ventolin prescription online (number of drinks per day). These were combined to form a total monthly consumption. For each behaviour, participants retrospectively reported levels in “the month before get ventolin prescription online the asthma outbreak” and then during the fieldwork period (May 2020).

Herein, we refer to these reference periods as before and during lockdown, respectively. In subsequent regression modelling, binary outcomes were created for all outcomes, chosen to capture high-risk groups in which there was sufficient variation across all cohort get ventolin prescription online and risk factor subgroups—sleep (1=<6 hours or >9 hours per night given its non-linear relation with health outcomes),38 39 exercise (1=2 or fewer days/week exercise), diet (1=2 or fewer portions of fruit and vegetables/day) and alcohol (1=≥14 drinks per week or 5 or more drinks per day. 0=lower frequency and/or consumption).40Risk factorsSocioeconomic position was indicated by childhood social class (at 10–14 years old), using the Registrar General’s Social Class scale—I (professional), II (managerial and technical), IIIN (skilled non-manual), IIIM (skilled manual), IV (partly-skilled) and V (unskilled) occupations. Highest educational attainment was also used, categorised into four groups as follows. Degree/higher, A levels/diploma, O Levels/GCSEs or none (for 2001c we used parents’ highest education as many were still undertaking education) get ventolin prescription online.

Financial difficulties were based on whether individuals (or their parents for 2001c) reported (prior to asthma treatment) as managing financially comfortably, all right, just about getting by and difficult. These ordinal indicators were converted into cohort-specific ridit scores to aid interpretation—resulting in relative or slope indices of inequality when used in regression models (ie, comparisons of the health difference comparing lowest with highest SEP).41 Ethnicity get ventolin prescription online was recorded as White and non-White—with analyses limited to the 1990c and 2001c owing to a lack of ethnic diversity in older cohorts. Gender was ascertained in the baseline survey in each cohort.Statistical analysesWe calculated average levels and distributions of each outcome before and during lockdown. Logistic regression models were used to examine how gender, ethnicity and SEP were related to each outcome, both before and during lockdown. Where the prevalence of the outcome differs across time, comparing results on the relative scale can impair get ventolin prescription online comparisons of risk factor–outcome associations (eg, identical ORs can reflect different magnitudes of associations on the absolute scale).42 Thus, we estimated absolute (risk) differences in outcomes by gender, SEP and ethnicity (the margins command in Stata following logistic regression).

Models examining ethnicity and SEP were gender adjusted. We conducted cohort-specific analyses get ventolin prescription online and conducted meta-analyses to assess pooled associations, formally testing for heterogeneity across cohorts (I2 statistic). To understand the changes which led to differing inequalities, we also tabulated calculated change in each outcome (decline, no change and increase) by each cohort and risk factor group. To confirm that the patterns of inequalities observed using binary outcomes was consistent with results using the entire distribution of each outcome, we additionally tabulated all outcome categories by cohort and risk factor group.To account for possible bias due to missing data, we weighted our analysis using weights constructed from logistic regression models—the outcome was response during the asthma treatment survey, and predictors were demographic, socioeconomic, household and individual-based predictors of non-response at earlier sweeps, based on previous work in these cohorts.37 43 44 We also used weights to account for the stratified survey designs of the 1946c, 1990c and 2001c. Stata V.15 get ventolin prescription online (StataCorp) was used to conduct all analyses.

Analytical syntax to facilitate result reproduction is provided online (https://github.com/dbann/asthma treatment_cohorts_health_beh).ResultsCohort-specific responses were as follows. 1946c. 1258 of 1843 (68%). 1958c. 5178 of 8943 (58%), 1970c.

4223 of 10 458 (40%). 1990c. 1907 of 9380 (20%). 2001c. 2645 of 9946 (27%).

The following factors, measured in prior data collections, were associated with increased likelihood of response in this asthma treatment dataset. Being female, higher education attainment, higher household income and more favourable self-rated health. Valid outcome data were available in both before and during lockdown periods for the following. Sleep, N=14 171. Exercise, N=13 997.

Alcohol, N=14 297. Fruit/vegetables, N=13 623.Overall changes and cohort differencesOutcomes before and during lockdown were each moderately highly positively correlated—Spearman’s R as follows. Sleep=0.55, exercise=0.58, alcohol (consumption frequency)=0.76 and fruit/vegetable consumption=0.81. For all outcomes, older cohorts were less likely to report change in behaviour compared with younger cohorts (online supplemental table 1).Supplemental materialThe average (mean) amount of sleep (hours per night) was either similar or slightly higher during compared with before lockdown. In each cohort, the variance was higher during lockdown (table 1)—this reflected the fact that more participants reported either reduced or increased amounts of sleep during lockdown (figure 1).

In 2001c compared with older cohorts, more participants reported increased amounts of sleep during lockdown (figure 1, online supplemental tables 1 and 2). Mean exercise frequency levels were similar during and before lockdown (table 1). As with sleep levels, the variance was higher during lockdown, reflecting both reduced and increased amounts of exercise during lockdown (figure 1, online supplemental table 2). In 2001c, a larger fraction of participants reported transitions to no alcohol consumption during lockdown than in older cohorts (table 1, online supplemental table 2). Fruit and vegetable intake was broadly similar before and during lockdown, although increases in consumption were most frequent in 2001c compared with older cohorts (figure 1, online supplemental table 1).View this table:Table 1 Participant characteristics.

Data from 5 British cohort studies36, 16–36, 1–15, no drinks per month." class="highwire-fragment fragment-images colorbox-load" rel="gallery-fragment-images-559648027" data-figure-caption="Before and during asthma treatment lockdown distributions of health-related behaviours, by cohort. Note. Colour version of the figure is available online - Pre-lockdown = pink. During Lockdown = light green. Dark green shows overlap, estimates are weighted to account for survey non-response.

Alcohol consumption was derived as >36, 16–36, 1–15, no drinks per month." data-icon-position data-hide-link-title="0">Figure 1 Before and during asthma treatment lockdown distributions of health-related behaviours, by cohort. Note. Colour version of the figure is available online - Pre-lockdown = pink. During Lockdown = light green. Dark green shows overlap, estimates are weighted to account for survey non-response.

Alcohol consumption was derived as >36, 16–36, 1–15, no drinks per month.Gender inequalitiesWomen had a higher risk than men of atypical sleep levels (ie, <6 or >9 hours), and such differences were larger during compared with before lockdown (pooled per cent risk difference during (men vs women, during lockdown. ˆ’4.2 (−6.4, –1.9), before. ˆ’1.9 (−3.7, –0.2). Figure 2). These differences were similar in each cohort (I2=0% and 11.6%respectively) and reflected greater change in female sleep levels during lockdown (online supplemental table 1).

Before lockdown, in all cohorts women undertook less exercise than men. During lockdown, this difference reverted to null (figure 2). This was due to relatively more women reporting increased exercise levels during lockdown compared with before (online supplemental table 1). Men had higher alcohol consumption than women, and reported lower fruit and vegetable intake. Effect estimates were slightly weaker during compared with before lockdown (figure 2).Differences in multiple health behaviours during asthma treatment lockdown (May 2020.

Right panels) compared with prior levels (left panels), according to gender (A), education attainment (B) and ethnicity (C). Meta-analyses of 5 cohort studies. Note. Estimates show the risk difference (RD) on the percentage scale and are weighted to account for survey non-response. Ridit scores represent the difference in risk of the highest versus lowest education." data-icon-position data-hide-link-title="0">Figure 2 Differences in multiple health behaviours during asthma treatment lockdown (May 2020.

Right panels) compared with prior levels (left panels), according to gender (A), education attainment (B) and ethnicity (C). Meta-analyses of 5 cohort studies. Note. Estimates show the risk difference (RD) on the percentage scale and are weighted to account for survey non-response. Ridit scores represent the difference in risk of the highest versus lowest education.Socioeconomic inequalitiesThose with lower education had higher risk of atypical sleep levels—this difference was larger and more consistently found across cohorts during compared with before lockdown (figure 2).

Lower education was also associated with lower exercise participation, and with lower fruit and vegetable intake (particularly strongly in 2001c), but not with alcohol consumption. Estimates of association were similar before and during lockdown (figure 2). Associations of childhood social class and adulthood financial difficulties with these outcomes were broadly similar to those for education attainment (online supplemental figure 1)—differences in sleep during lockdown were larger than before, and lower childhood social class was more strongly related to lower exercise participation during lockdown (online supplemental figure 1), and with lower fruit and vegetable intake (particularly in 2001c).Ethnic inequalitiesEthnic minorities had higher risk of atypical sleep levels than white participants, with larger effect sizes during compared with before lockdown (figure 2, online supplemental table 1). Ethnic minorities had lower exercise levels during but not before lockdown—pooled per cent risk difference during (ethnic minority vs white). 9.0 (1.8, 16.3.

I2=0%. Figure 2). Ethnic minorities also had higher risk of lower fruit and vegetable intake, with stronger associations during lockdown (figure 2). In contrast, ethnic minorities had lower alcohol consumption, with stronger effect sizes before lockdown than during (figure 2).DiscussionMain findingsUsing data from five national British cohort studies, we estimated the change in multiple health behaviours between before and during asthma treatment lockdown periods in the UK (May 2020). Where change in these outcomes was identified, it occurred in both directions—that is, shifts from the middle part of the distribution to both declines and increases in sleep, exercise and alcohol use.

In the youngest cohort (2001c), the following shifts were more evident. Increases in exercise, fruit and vegetable intake, and sleep, and reduced alcohol consumption frequency. Across all outcomes, older cohorts were less likely to report changes in behaviour. Our findings suggest—for most outcomes measured—a potential widening of inequalities in health-impacting behavioural outcomes which may have been caused by the asthma treatment lockdown.Comparison with other studiesIn our study, the youngest cohort reported increases in sleep during lockdown—similar findings of increased sleep have been reported in many13 17 18 24 but not all8 previous studies. Both too much and too little sleep may reflect, and be predictive of, worse mental and physical health.38 39 In this sense, the increasing dispersion in sleep we observed may reflect the negative consequences of asthma treatment and lockdown.

Women, those of lower SEP and ethnic minorities were all at higher risk of atypical sleep levels. It is possible that lockdown restrictions and subsequent increases in stress—related to health, job and family concerns—have affected sleep across multiple generations and potentially exacerbated such inequalities. Indeed, work using household panel data in the UK has observed marked increases in anxiety and depression in the UK during lockdown that were largest among younger adults.4Our findings on exercise add to an existing but somewhat mixed evidence base. Some studies have reported declines in both self-reported12 23 and accelerometery-assessed physical activity,19 yet this is in contrast to others which report an increase,22 and there is corroborating evidence for increases in some forms of physical activity since online searches for exercise and physical activity appear to have increased.21 As in our study, another also reported that men had lower exercise levels during lockdown.20 While we cannot be certain that our findings reflect all changes to physical activity levels—lower intensity exercises were not assessed nor was activity in other domains such as in work or travel—the widening inequalities in ethnic minority groups may be a cause of public health concern.As for the impact of the lockdown on alcohol consumption, concern was initially raised over the observed rises in alcohol sales in stores at the beginning of the ventolin in the UK45 and elsewhere. Our findings suggest decreasing consumption particularly in the younger cohort.

Existing studies appear largely mixed, some suggesting increases in consumption,9 16 26 with others reporting decreases11 12 23 25. Others also report increases, yet use instruments which appear to particularly focus on capturing increases and not declines.8 10 Different methodological approaches and measures used may account for inconsistent findings across studies, along with differences in the country of origin and characteristics of the sample. The closing of pubs and bars and associated reductions in social drinking likely underlies our finding of declines in consumption among the youngest cohort. Loss of employment and income may have also particularly affected purchasing power in younger cohorts (as suggested in the higher reports of financial difficulties (table 1)), thereby affecting consumption. Increases in fruit and vegetable consumption observed in this cohort may have also reflected the considerable social changes attributable to lockdown, including more regular food consumption at home.

However, in our study only positive aspects of diet (fruit and veg consumption) were captured—we did not capture information on volume of food, snacking and consumption of unhealthy foods. Indeed, one study reported simultaneous increases in consumption of fruit and vegetables and high sugar snacks.11Further research using additional waves of data collection is required to empirically investigate if the changes and inequalities observed in the current study persist into the future. If the changes persist and/or widen, given the relevance of these behaviours to a range of health outcomes including chronic conditions, asthma treatment consequences and years of healthy life lost, the public health implications of these changes may be long-lasting.Methodological considerationsWhile our analyses provide estimates of change in multiple important outcomes, findings should be interpreted in the context of the limitations of this work, with fieldwork necessarily undertaken rapidly. First, self-reported measures were used—while the two reference periods for recall were relatively close in time, comparisons of change in behaviour may have been biased by measurement error and reporting biases. Further, single measures of each behaviour were used which do not fully capture the entire scope of the health-impacting nature of each behaviour.

For example, exercise levels do not capture less intensive physical activities, nor sedentary behaviour. While fruit and vegetable intake is only one component of diet. As in other studies investigating changes in such outcomes, we are unable to separate out change attributable to asthma treatment lockdown from other causes—these may include seasonal differences (eg, lower physical activity levels in the pre-asthma treatment winter months), and other unobserved factors which we were unable to account for. If these factors affected the sub-groups we analysed (gender, SEP, ethnicity) equally, our analysis of risk factors of change would not be biased due to this. We acknowledge that quantifying change and examining its determinants is notoriously methodologically challenging—such considerations informed our analytical approach (eg, to avoid spurious associations, we did not adjust for ‘baseline’ (pre-lockdown) measures when examining outcomes during lockdown).46As in other web surveys,4 response rates were generally low—while the longitudinal nature of the cohorts enable predictors of missingness to be accounted for (via sample weights),43 44 we cannot fully exclude the possibility of unobserved predictors of missing data influencing our results.

Response rates were lowest in the youngest cohorts—while the direction and magnitude of any resulting bias may be risk factor and outcome specific, unobserved contributors to missing data could feasibly bias cross-cohort comparisons undertaken. Finally, we investigated ethnicity using a binary categorisation to ensure sufficient sample sizes for comparisons—we were likely underpowered to investigate differences across the multiple diverse ethnic groups which exist. This warrants future investigation given the substantial heterogeneity within these groups and likely differences in behavioural outcomes.ConclusionOur findings highlight the multiple changes to behavioural outcomes that may have occurred due to asthma treatment lockdown, and the differential impacts—across generation, gender, socioeconomic disadvantage (in early and adult life) and ethnicity. Such changes require further monitoring given their possible implications to population health and the widening of health inequalities.What is already known on this subjectBehaviours are important contributors to population health and its equity. asthma treatment and consequent policies (eg, social distancing) are likely to have influenced such behaviours, with potential longer-term consequences to population health and its equity.

However, the existing evidence base is inconsistent and challenging to interpret given likely heterogeneity across place, time and due to differences in the outcomes examined.What this study addsWe added to the rapidly emerging evidence base on the potential consequences of asthma treatment on multiple behavioural determinants of health. We compared multiple behaviours before and during lockdown (May 2020), across five nationally representative cohort studies of different ages (19–74 years), and examined differences across multiple health equity stratifiers. Gender, socioeconomic factors across life, and ethnicity. Our findings provide new evidence on the multiple changes to behavioural outcomes linked to lockdown, and the differential impacts across generation, gender, socioeconomic circumstances across life and ethnicity. Lockdown appeared to widen some (but not all) forms of health inequality.Ethics statementsPatient consent for publicationNot required.Ethics approvalResearch ethics approval was obtained from the UCL Institute of Education Research Ethics Committee (ref.

REC1334).AcknowledgmentsWe thank the Survey, Data, and Administrative teams at the Centre for Longitudinal Studies and Unit for Lifelong Health and Ageing, UCL, for enabling the rapid asthma treatment data collection to take place. We also thank Professors Rachel Cooper and Mark Hamer for helpful discussions during the asthma treatment questionnaire design period. DB is supported by the Economic and Social Research Council (grant no. ES/M001660/1) and Medical Research Council (MR/V002147/1). DB and AV are supported by The Academy of Medical Sciences/Wellcome Trust (“Springboard Health of the Public in 2040” award.

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GET STARTED Log In | Learn More What is get ventolin prescription online it?. STAT+ is STAT's premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.

What's get ventolin prescription online included?. Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr.Hired someone new and exciting?. Promoted a rising star?.

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Our award-winning team covers news on Wall Street, policy developments in Washington, early science get ventolin prescription online breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond. What's included?. Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr.And so, another working week will soon draw to a close.

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Ventolin gsk

About This TrackerThis tracker provides the number of confirmed cases and deaths from ventolin evohaler for sale novel asthma by country, the trend in confirmed case and ventolin gsk death counts by country, and a global map showing which countries have confirmed cases and deaths. The data are drawn from the Johns Hopkins University (JHU) asthma Resource Center’s asthma treatment Map and the World Health Organization’s (WHO) asthma Disease (asthma treatment-2019) situation reports.This tracker will be updated regularly, as new data are released.Related Content. About asthma treatment asthmaIn late 2019, a new asthma emerged ventolin gsk in central China to cause disease in humans. Cases of this disease, known as asthma treatment, have since been reported across around the globe.

On January 30, 2020, the World Health Organization (WHO) declared the ventolin represents a public health emergency of international concern, and on January ventolin gsk 31, 2020, the U.S. Department of Health and Human Services declared it to be a health emergency for the United States.Key PointsOn January 23, 2017, President Donald Trump reinstated and expanded the Mexico City Policy via presidential memorandum, renaming it “Protecting Life in Global Health Assistance.” This explainer provides an overview of the policy, including its history, changes over time, and current application.First announced in 1984 by the Reagan administration, the policy has been rescinded and reinstated by subsequent administrations along party lines and has now been in effect for 19 of the past 34 years.The policy requires foreign non-governmental organizations (NGOs) to certify that they will not “perform or actively promote abortion as a method of family planning” using funds from any source (including non-U.S. Funds) as a condition of receiving U.S ventolin gsk. Government global family planning assistance and, as of Jan.

23, 2017, most ventolin gsk other U.S. Global health assistance.The Trump administration’s application of the policy extends to the vast majority of U.S. Bilateral global health ventolin gsk assistance, including funding for HIV under PEPFAR, maternal and child health, malaria, nutrition, and other programs. This marks a significant expansion of its scope, potentially encompassing $7.3 billion in FY 2020, to the extent that such funding is ultimately provided to foreign NGOs, directly or indirectly (family planning assistance accounts for approximately $600 million of that total).Additionally, as a result of a March 2019 policy announcement and subsequent information released in June 2019, the policy, for the first time, prohibits foreign NGOs who accept the policy from providing any financial support using any source of funds and for any purpose to other foreign NGOs that perform or actively promote abortion as a method of family planning.

This greatly ventolin gsk extends its reach to other areas of U.S. Development assistance beyond global health and to other non-U.S. Funding streams.More recently, in September 2020, a proposed rule to extend the policy to ventolin gsk contracts was published. If finalized, it would greatly extend the reach of the policy beyond grants and cooperative agreements to also include contracts.KFF analyses have found that:more than half of the countries in which the U.S.

Provides bilateral global health assistance allow for legal abortion in at least one ventolin gsk case not permitted by the policy (analysis). Andhad the expanded policy been in effect during the FY 2013 – FY 2015 period, at least 1,275 foreign NGOs would have been subject to the policy (analysis).What is the Mexico City Policy?. The Mexico City Policy is a U.S ventolin gsk. Government policy that – when in effect – has required foreign NGOs to certify that they will not “perform or actively promote abortion as a method of family planning” using funds from any source (including non-U.S.

Funds) as ventolin gsk a condition of receiving U.S. Global family planning assistance and, as of Jan. 23, 2017, most other U.S ventolin gsk. Global health assistance.The policy was first announced by the Reagan administration at the 2nd International Conference on Population, which was held in Mexico City, Mexico, on August 6-14, 1984 (hence its name.

See Box ventolin gsk 1). Under the Trump administration, the policy has been renamed “Protecting Life in Global Health Assistance” (PLGHA). Among opponents, it is also known as the “Global Gag Rule,” because among other activities, ventolin gsk it prohibits foreign NGOs from using any funds (including non-U.S. Funds) to provide information about abortion as a method of family planning and to lobby a foreign government to legalize abortion.

€œ[T]he United States does not consider abortion an acceptable element of family planning programs and will no longer contribute to those of which it is a ventolin gsk part. €¦[T]he United States will no longer contribute to separate nongovernmental organizations which perform or actively promote abortion as a method of family planning in other nations.”When first instituted in 1984, the Mexico City Policy marked an expansion of existing legislative restrictions that already prohibited U.S. Funding for abortion internationally, with some exceptions (see ventolin gsk below). Prior to the policy, foreign NGOs could use non-U.S.

Funds to engage in certain voluntary abortion-related activities as long as they ventolin gsk maintained segregated accounts for any U.S. Money received, but after the Mexico City Policy was in place, they were no longer permitted to do so if they wanted to receive U.S. Family planning ventolin gsk assistance.The Trump administration’s application of the policy to the vast majority of U.S. Bilateral global health assistance, including funding for HIV under the U.S.

President’s Emergency Plan for AIDS Relief (PEPFAR), maternal and child health, malaria, nutrition, and other programs, marks a ventolin gsk significant expansion of its scope, potentially encompassing $7.3 billion in FY 2020, to the extent that such funding is ultimately provided to foreign NGOs, directly or indirectly (family planning assistance accounted for approximately $600 million of that total). The Administration’s more recent extension of the policy to include any financial support (health or otherwise) provided by foreign NGOs for any purpose to other foreign NGOs that perform or actively promote abortion as a method of family planning is likely to encompass significant additional funding.When has it been in effect?. The Mexico City Policy has been in effect for 19 of the past 34 years, primarily through executive action, and has been instated, rescinded, and reinstated by presidential administrations along party lines (see Table 1).The policy was first instituted in 1984 (taking effect in 1985) by President Ronald Reagan and continued to be in effect through President George H.W. Bush’s administration ventolin gsk.

It was rescinded by President Bill Clinton in 1993 (although it was reinstated legislatively for one year during his second term. See below) ventolin gsk. The policy was reinstated by President George W. Bush in ventolin gsk 2001 and then rescinded by President Barack Obama in 2009.

It is currently in effect, having been reinstated by President Trump in 2017. YearsIn Effect? ventolin gsk. Presidential Administration (Party Affiliation)Executive (E) or Congressional (C) Action?. 1985-1989YesReagan (R)E1989-1993YesBush (R)E1993-1999 Sept.NoClinton (D)E1999 Oct.-2000 Sept.Yes*Clinton ventolin gsk (D)C2000 Oct.-2001NoClinton (D)E2001-2009YesBush (R)E2009-2017NoObama (D)E2017-presentYesTrump (R)ENOTES.

Shaded blue indicate periods when policy was in effect. * There was a temporary, one-year legislative imposition of the policy, which included a ventolin gsk portion of the restrictions in effect in other years and an option for the president to waive these restrictions in part. However, if the waiver option was exercised (for no more than $15 million in family planning assistance), then $12.5 million of this funding would be transferred to maternal and child health assistance. The president did exercise ventolin gsk the waiver option.SOURCES.

€œPolicy Statement of the United States of America at the United Nations International Conference on Population (Second Session), Mexico City, Mexico, August 6-14, 1984,” undated. Bill Clinton ventolin gsk Administration, “Subject. AID Family Planning Grants/Mexico City Policy,” Memorandum for the Acting Administrator of the Agency for International Development, January 22, 1993, Clinton White House Archives, https://clintonwhitehouse6.archives.gov/1993/01/1993-01-22-aid-family-planning-grants-mexico-city-policy.html. FY 2000 ventolin gsk Consolidated Appropriations Act, P.L.

106-113. George W ventolin gsk. Bush Administration, “Subject. Restoration of the Mexico City Policy,” Memorandum for the Administrator of the United States Agency for International Development, January 22, 2001, Bush Administration White House Archives, ventolin gsk https://georgewbush-whitehouse.archives.gov/news/releases/20010123-5.html.

€œSubject. Restoration of the Mexico ventolin gsk City Policy,” Memorandum for the Administrator of the United States Agency for International Development, March 28, 2001, Federal Register, https://www.federalregister.gov/documents/2001/03/29/01-8011/restoration-of-the-mexico-city-policy. George W. Bush Administration, ventolin gsk “Subject.

Assistance for Voluntary Population Planning,” Memorandum for the Secretary of State, August 29, 2003, Bush Administration White House Archives, http://georgewbush-whitehouse.archives.gov/news/releases/2003/08/20030829-3.html. Barack Obama Administration, “Mexico City Policy and Assistance for Voluntary Population Planning,” Memorandum for the Secretary of State, the Administrator of the United States Agency ventolin gsk for International Development, January 23, 2009, Obama White House Archives, https://obamawhitehouse.archives.gov/the-press-office/mexico-city-policy-and-assistance-voluntary-population-planning. White House, “The Mexico City Policy,” Memorandum for the Secretary of State, the Secretary of Health and Human Services, the Administrator of the Agency for International Development, Jan. 23, 2017, https://www.whitehouse.gov/the-press-office/2017/01/23/presidential-memorandum-regarding-mexico-city-policy.How is ventolin gsk it instituted (and rescinded)?.

The Mexico City Policy has, for the most part, been instituted or rescinded through executive branch action (typically via presidential memoranda). While Congress has ventolin gsk the ability to institute the policy through legislation, this has happened only once in the past. A modified version of the policy was briefly applied by Congress during President Clinton’s last year in office as part of a broader arrangement to pay the U.S. Debt to the United Nations ventolin gsk.

(At that time, President Clinton was able to partially waive the policy’s restrictions.) Other attempts to institute the policy through legislation have not been enacted into law, nor have legislative attempts to overturn the policy. See Table 1.Who does the policy apply ventolin gsk to?. The policy, when in effect, applies to foreign NGOs as a condition for receiving U.S. Family planning support and, now, other global health assistance, either directly (as the main – or prime – recipient of U.S.

Funding) or indirectly (as a recipient ventolin gsk of U.S. Funding through an agreement with the prime recipient. Referred to ventolin gsk as a sub-recipient). Specifically, a foreign NGO “recipient agrees that it will not, during the term of this award, perform or actively promote abortion as a method of family planning in foreign countries or provide financial support to any other foreign non-governmental organization that conducts such activities.”Foreign NGOs include:international NGOs that are based outside the U.S.,regional NGOs that are based outside the U.S., andlocal NGOs in assisted countries.U.S.

NGOs, while not directly subject to the Mexico City Policy, must also agree to ensure that they do not provide funding to any foreign NGO ventolin gsk sub-recipients unless those sub-recipients have first certified adherence to the policy. Specifically, a U.S. NGO “recipient (A) agrees that it will not furnish health assistance under this award to any foreign non-governmental organization that performs or actively promotes abortion as a method of family ventolin gsk planning in foreign countries. And (B) further agrees to require that such sub-recipients do not provide financial support to any other foreign non-governmental organization that conducts such activities.”As in the past, the current policy does not apply to funding provided by the U.S.

Government to foreign governments (national or sub-national), public international organizations, and other multilateral entities, such as the Global ventolin gsk Fund to Fight AIDS, Tuberculosis and Malaria and Gavi, the treatment Alliance. However, this funding is subject to the policy if it flows through a foreign NGO that has accepted the policy. See “What is ‘financial support’? ventolin gsk. € below.To what assistance does it apply?.

In the past, foreign NGOs have been required to adhere to the Mexico City Policy – when it was in effect – as a condition of receiving support through certain U.S ventolin gsk. International funding streams. Family planning ventolin gsk assistance through the U.S. Agency for International Development (USAID) and, beginning in 2003, family planning assistance through the U.S.

Department of State ventolin gsk. In the 2003 memorandum announcing the policy’s expansion to include the Department of State, President Bush stated that the policy did not apply to funding for global HIV/AIDS programs and that multilateral organizations that are associations of governments are not included among “foreign NGOs.”The current policy, reinstated in 2017, applies to the vast majority of U.S. Bilateral global health assistance furnished ventolin gsk by all agencies and departments. “Assistance” includes “the provision of funds, commodities, equipment, or other in-kind global health assistance.” Specifically, the expanded policy applies to nearly all bilateral global health assistance, including.

family planning and reproductive healthfor the first time:maternal and child health (including household-level water, sanitation, and hygiene (WASH))nutritionHIV under PEPFARtuberculosismalaria under the President’s Malaria Initiative (PMI)neglected tropical diseasesglobal health securitycertain types of research activitiesThe policy applies to ventolin gsk the assistance described above that is appropriated directly to three agencies and departments. USAID. The Department of State, including the Office of the Global AIDS Coordinator, ventolin gsk which oversees and coordinates U.S. Global HIV funding under PEPFAR.

And for the first time, the Department of Defense ventolin gsk (DoD). When such funding is transferred to another agency, including the Centers for Disease Control (CDC) and the National Institutes of Health (NIH), it remains subject to the policy, to the extent that such funding is ultimately provided to foreign NGOs, directly or indirectly.The policy applies to three types of funding agreements for such assistance. Grants. Cooperative agreements.

And, for the first time, contracts, pending necessary rule-making that would be needed to do so (a proposed rule to accomplish this was published in September 2020).The policy does not apply to U.S. Assistance for. Water supply and sanitation activities, which is usually focused on infrastructure and systems. Humanitarian assistance, including activities related to migration and refugee assistance activities as well as disaster and humanitarian relief activities.

The American Schools and Hospitals Abroad (ASHA) program. And Food for Peace (FFP). However, this funding is subject to the policy if it flows through a foreign NGO that has accepted the policy. See “What is ‘financial support’?.

€ below.What activities are prohibited? http://ginagarza.com/?page_id=13. The policy prohibits foreign NGOs that receive U.S. Family planning assistance and, now, most other U.S. Bilateral global health assistance from using funds from any source (including non-U.S.

Funds) to “perform or actively promote abortion as a method of family planning.” In addition to providing abortions with non-U.S. Funds, restricted activities also include the following:providing advice and information about and offering referral for abortion – where legal – as part of the full range of family planning options,promoting changes in a country’s laws or policies related to abortion as a method of family planning (i.e., engaging in lobbying), andconducting public information campaigns about abortion as a method of family planning.The prohibition of these activities are why the policy has been referred to by its critics as the “Global Gag Rule.”Additionally, for the first time, the policy prohibits foreign NGOs from providing any financial support with any source of funds (including non-U.S. Funding) and for any purpose to other foreign NGOs that perform or actively promote abortion as a method of family planning. See “What is “financial support?.

€ below.The policy, however, does not prohibit foreign NGOs from:providing advice and information about, performing, or offering referral for abortion in cases where the pregnancy has either posed a risk to the life of the mother or resulted from incest or rape. Andresponding to a question about where a safe, legal abortion may be obtained when a woman who is already pregnant clearly states that she has already decided to have a legal abortion (passively providing information, versus actively providing medically-appropriate information).In addition, the expanded policy does not apply to healthcare providers who have an affirmative duty required under local law to provide counseling about and referrals for abortion as a method of family planning.Does it restrict direct U.S. Funding for abortion overseas?. U.S.

Funding for abortion is already restricted under several provisions of the law. Specifically, before the Mexico City Policy was first announced in 1984, U.S. Law already prohibited the use of U.S. Aid:to pay for the performance of abortion as a method of family planning or to motivate or coerce any person to practice abortion (the Helms Amendment, 1973, to the Foreign Assistance Act);for biomedical research related to methods of or the performance of abortion as a means of family planning (the Biden Amendment, 1981, to the Foreign Assistance Act).

Andto lobby for or against abortion (the Siljander Amendment, first included in annual appropriations in 1981 and included each year thereafter).Then, shortly after the policy was announced in 1984, the Kemp-Kasten Amendment was passed in 1985, prohibiting the use of U.S. Aid to fund any organization or program, as determined by the president, that supports or participates in the management of a program of coercive abortion or involuntary sterilization (it is now included in annual appropriations).Before the Mexico City Policy, U.S. Aid recipients could use non-U.S. Funds to engage in certain abortion-related activities but were required to maintain segregated accounts for U.S.

Assistance. The Mexico City Policy reversed this practice. No longer were foreign NGOs allowed to use non-U.S. Funds, maintained in segregated accounts, for voluntary abortion-related activities if they wished to continue to receive or be able to receive U.S.

Family planning funds.Does the policy prohibit post-abortion care?. The Mexico City Policy does not restrict the provision of post-abortion care, which is a supported activity of U.S. Family planning assistance. Whether or not the Mexico City Policy is in effect, recipients of U.S.

Family planning assistance are allowed to use U.S. And non-U.S. Funding to support post-abortion care, no matter the circumstances of the abortion (whether it was legal or illegal).What has been the impact of the policy?. Several studies have looked at the impact of the policy.

A 2011 quantitative analysis by Bendavid, et. Al, found a strong association between the Mexico City Policy and abortion rates in sub-Saharan Africa. This study was recently updated to include several more years of data, again identifying a strong association. Specifically, the updated study found that during periods when the policy was in place, abortion rates rose by 40% in countries with high exposure to the Mexico City Policy compared to those with low exposure, while the use of modern contraceptives declined by 14% and pregnancies increased by 12% in high exposure compared to low exposure countries.

In other words, it found patterns that “strengthen the case for the role played by the policy” in “a substantial increase in abortions across sub-Saharan Africa among women affected by the U.S. Mexico City Policy … [and] a corresponding decline in the use of modern contraception and increase in pregnancies,” likely because foreign NGOs that declined U.S. Funding as a result of the Mexico City Policy – often key providers of women’s health services in these areas – had fewer resources to support family planning services, particularly contraceptives. Increased access to and use of contraception have been shown to be key to preventing unintended pregnancies and thereby reducing abortion, including unsafe abortion.

The study also found patterns that “suggest that the effects of the policy are reversible” when the policy is not in place.Additionally, there has been anecdotal evidence and qualitative data on the impact of the policy, when it has been in force in the past, on the work of organizations that have chosen not to agree to the policy and, therefore, forgo U.S. Funding that had previously supported their activities. For example, they have reported that they have fewer resources to support family planning and reproductive health services, including family planning counseling, contraceptive commodities, condoms, and reproductive cancer screenings.While it is likely too early to assess the full effects of the current policy on NGOs and the individuals they serve, as the policy is applied on a rolling basis as new funding agreements or modifications to existing agreements are made, some early data are available. Several early qualitative and quantitative studies have been released, and at least one long-term, quantitative assessment is underway.

Additionally, an official assessment by the U.S. Department of State on implementation during the first six months of the policy has been released (see below). This review acknowledged that it took “place early in the policy’s implementation, when affected U.S. Government departments and agencies have added a significant portion of the funding affected by the policy to grants and cooperative agreements only recently [i.e., after the period the review examined].

A follow-on analysis would allow an opportunity to address one of the primary concerns presented in feedback from third-party stakeholder organizations, namely that six months is insufficient time to gauge the impacts of” the policy.Nonetheless, it is already clear that the reinstated and expanded version of the policy applies to a much greater amount of U.S. Global health assistance, and greater number of foreign NGOs, across many program areas. KFF has found that more than half (37) of the 64 countries that received U.S. Bilateral global health assistance in FY 2016 allow for legal abortion in at least one case not permitted by the policy and that had the expanded Mexico City Policy been in effect during the FY 2013 – FY 2015 period, at least 1,275 foreign NGOs would have been subject to the policy.

In addition, at least 469 U.S. NGOs that received U.S. Global health assistance during this period would have been required to ensure that their foreign NGO sub-recipients were in compliance. Additional foreign NGOs are likely to be impacted by the policy due to the revised interpretation of “financial support” announced in March 2019 and implemented beginning June 2019.

See “What is ‘financial support’?. € below.A report released in March 2020 by the U.S. Government Accountability Office (GAO) provided new information on the number of projects (awards) and NGOs affected. It found that from May 2017 through FY 2018:the policy had been applied to over 1,300 global health projects, with the vast majority of these through USAID and CDC, andNGOs declined to accept the policy in 54 instances, totaling $153 million in declined funding – specifically, seven prime awards amounting to $102 million and 47 sub-awards amounting to $51 million (more than two-thirds of sub-awards were intended for Africa) – across USAID and CDC.

The Department of State and DoD did not identify any instances where NGOs declined to accept the policy conditions.What have the U.S. Government’s reviews of the policy found?. The U.S. Government has published two reviews of the policy to date, with the first examining the initial six months of the policy released in February 2018 and the second examining the first 18 months of the policy released in August 2020.First ReviewIn February 2018, the Department of State announced the findings of an initial six-month review of implementation of the policy through the end of FY 2017 (September 2017).

The report directed agencies to provide greater support for improving understanding of implementation among affected organizations and provided guidance to clarify terms included in standard provisions of grants and cooperative agreements. In the six-month review report, the Department of State report identified a number of “actions” for implementing agencies, such as a need for:more central and field-based training and implementation tools,a clearer explanation of termination of awards for NGOs found to be in violation of the policy, anda clarification of “financial support,” which was not defined in the standard provisions (see “What is financial support?. € below).The six month review also identified the number of affected agreements with prime implementing partners and the number of those that have accepted the Mexico City Policy as part of their agreements through September 2017 (see Table 2). U.S.

Agency or DepartmentPolicy Implementation DateOverall # of Grants and Cooperative Agreements with Global Health Assistance FundingOf Overall #:(From the Policy Implementation Date through 9/30/2017)# That Received New Funding and Accepted Policy# That Received New Funding and Declined to Accept Policy^# That Had Not Received New Funding YetUSAIDMay 15, 20175804193158State*May 15, 2017142108034HHS+May 31, 20174991600339DoDMay 15, 20177742134TOTAL12987294565NOTES. * reflects PEPFAR funding implemented through the Department of State. Other departments and agencies implement the majority of PEPFAR funding. + At HHS agencies, only certain assistance funding transferred from USAID, State, and DoD are subject to the policy.

^ As of September 30, 2017, USAID reported it was aware of three centrally funded prime partners, and 12 sub-awardee implementing partners, that declined to agree to the Protecting Life in Global Health Assistance (PLGHA) terms in their awards. DoD reported that one DoD partner, a U.S. NGO, declined to agree in one country but accepted the PLGHA standard provision in other countries. And HHS reported that no HHS partners declined to agree.SOURCES.

KFF analysis of data from Department of State, “Protecting Life in Global Health Assistance Six-Month Review,” report, Feb. 6, 2018, https://www.state.gov/protecting-life-in-global-health-assistance-six-month-review/.Second ReviewOn August 17, 2020, the Department of State released its second review of the policy, updating its initial six-month review (as an action item in the six-month review report, the department stated it would “conduct a further review of implementation of the policy by December 15, 2018, when more extensive experience will enable a more thorough examination of the benefits and challenges”). The long-anticipated review, which examines the period from May 2017 through September 2018, found:the awards declined spanned a variety of program areas, including family planning and reproductive health (FP/RH), HIV and AIDS (HIV/AIDS), maternal and child health (MCH), tuberculosis (TB), and nutrition, in addition to cross-cutting awards;the awards declined spanned geographic areas but many were for activities in sub-Saharan Africa;agencies and departments made efforts to transition projects to another implementer in order to minimize disruption. Butnevertheless, among USAID awards involving health service delivery where prime and sub-award recipients declined to accept the policy, gaps or disruptions in service delivery were sometimes reported.The second review also identified the number of affected agreements with prime implementing partners and the number of those that have accepted the Mexico City Policy as part of their agreements through September 2018 (see Table 3).

U.S. Agency or DepartmentPolicy Implementation Date# of Grants and Cooperative Agreements with Global Health Assistance Funding# of Prime Awardees That Declined to Accept Policy^USAIDMay 15, 20174866State*May 15, 20173350HHS+May 31, 20174661DoDMay 15, 2017531TOTAL13408NOTES. * reflects PEPFAR funding implemented through the Department of State. Other departments and agencies implement the majority of PEPFAR funding.

+ At HHS agencies, only certain assistance funding transferred from USAID, State, and DoD are subject to the policy. ^ As of September 30, 2018, USAID reported it was aware of six centrally funded prime partners, and 47 sub-awardee implementing partners, that declined to agree to the Protecting Life in Global Health Assistance (PLGHA) terms in their awards. DoD reported that one DoD partner, a U.S. NGO, declined to agree in one country but accepted the PLGHA standard provision in other countries.

And HHS reported that one HHS partner declined to agree.SOURCES. KFF analysis of data from Department of State, “Review of the Implementation of the Protecting Life in Global Health Assistance Policy ,” report, Aug. 17, 2020, https://www.state.gov/wp-content/uploads/2020/08/PLGHA-2019-Review-Final-8.17.2020-508.pdf, and Department of State, “Protecting Life in Global Health Assistance Six-Month Review,” report, Feb. 6, 2018, https://www.state.gov/protecting-life-in-global-health-assistance-six-month-review/.Additionally, the review reports that 47 sub-awardees, all under USAID awards, declined to accept the policy.

It is important to note that the review also states that information on sub-awards is not systematically collected by departments and agencies and that DoD was not able to collect information on sub-awards.What is “financial support”?. In February 2018, in the initial six-month review issued when Secretary of State Tillerson led the department, the Department of State report included an “action” statement to clarify the definition of “financial support” as used in the standard provisions for grants and cooperative agreements. At issue was whether it applied more narrowly to certain funding provided by foreign NGOs (i.e., funding other than U.S. Global health funding) to other foreign NGOs specifically for the purpose of performing or actively promoting abortion as a method of family planning or if it applied more broadly to certain funding provided by foreign NGOs to other foreign NGOs for any purpose, if that foreign NGO happened to perform or actively promote abortion as a method of family planning.

The State Department clarified that it was the more narrow interpretation.However, on March 26, 2019, Secretary of State Pompeo reversed this interpretation, announcing further “refinements” to the policy to clarify that it applied to the broader definition of financial support. Specifically, under the policy, U.S.-supported foreign NGOs agree to not provide any financial support (global health-related as well as other support), no matter the source of funds, to any other foreign NGO that performs or actively promotes abortion as a method of family planning. In June 2019, USAID provided additional information to reflect this broader interpretation of the standard provisions.This marks the first time the policy has been applied this broadly, as it can now affect funding provided by other donors (such as other governments and foundations) and non-global health funding provided by the U.S. Government for a wide range of purposes if this funding is first provided to foreign NGOs who have accepted the policy (as recipients of U.S.

Global health assistance) that then in turn provide that donor or U.S. Non global health funding for any purpose to foreign NGOs that perform or actively promote abortion as a method of family planning. For example, under the prior interpretation, a foreign NGO recipient of U.S. Global health funding could not provide any non-U.S.

Funding to another foreign NGO to perform or actively promote abortion as a method of family planning but could provide funding for other activities, such as education, even if the foreign NGO carried out prohibited activities. Under the broader interpretation, a foreign NGO could not provide any non-U.S. Funding for any activity to a foreign NGO that carried out prohibited activities. Similarly, while under the prior interpretation a foreign NGO recipient of U.S.

Global health funding could provide other U.S. Funding (such as humanitarian assistance) to another foreign NGO for non-prohibited activities, even if the foreign NGO carried out prohibited activities, now under the broader interpretation, it could not do so.What are the next steps in implementing the expanded policy?. The policy went into effect in May 2017 (see Table 2), although it is applied on a rolling basis, as new funding agreements and modifications to existing agreements occur. While it applies to all grants and cooperative agreements, the Trump administration has indicated that it intends the policy to apply to contracts, which would require a rule-making process (it began this process by publishing a proposed rule in September 2020)..

About This TrackerThis tracker provides the number of confirmed get ventolin prescription online cases and deaths from novel asthma by country, the trend in confirmed case and death counts by country, and a global map showing which countries have confirmed cases and deaths. The data are drawn from the Johns Hopkins University (JHU) asthma Resource Center’s asthma treatment Map and the World Health Organization’s (WHO) asthma Disease (asthma treatment-2019) situation reports.This tracker will be updated regularly, as new data are released.Related Content. About asthma treatment asthmaIn late 2019, a new asthma emerged in central China to cause get ventolin prescription online disease in humans.

Cases of this disease, known as asthma treatment, have since been reported across around the globe. On January get ventolin prescription online 30, 2020, the World Health Organization (WHO) declared the ventolin represents a public health emergency of international concern, and on January 31, 2020, the U.S. Department of Health and Human Services declared it to be a health emergency for the United States.Key PointsOn January 23, 2017, President Donald Trump reinstated and expanded the Mexico City Policy via presidential memorandum, renaming it “Protecting Life in Global Health Assistance.” This explainer provides an overview of the policy, including its history, changes over time, and current application.First announced in 1984 by the Reagan administration, the policy has been rescinded and reinstated by subsequent administrations along party lines and has now been in effect for 19 of the past 34 years.The policy requires foreign non-governmental organizations (NGOs) to certify that they will not “perform or actively promote abortion as a method of family planning” using funds from any source (including non-U.S.

Funds) as get ventolin prescription online a condition of receiving U.S. Government global family planning assistance and, as of Jan. 23, 2017, most other U.S get ventolin prescription online.

Global health assistance.The Trump administration’s application of the policy extends to the vast majority of U.S. Bilateral global health assistance, including funding for HIV under PEPFAR, maternal and get ventolin prescription online child health, malaria, nutrition, and other programs. This marks a significant expansion of its scope, potentially encompassing $7.3 billion in FY 2020, to the extent that such funding is ultimately provided to foreign NGOs, directly or indirectly (family planning assistance accounts for approximately $600 million of that total).Additionally, as a result of a March 2019 policy announcement and subsequent information released in June 2019, the policy, for the first time, prohibits foreign NGOs who accept the policy from providing any financial support using any source of funds and for any purpose to other foreign NGOs that perform or actively promote abortion as a method of family planning.

This greatly extends its reach to other areas of U.S get ventolin prescription online. Development assistance beyond global health and to other non-U.S. Funding streams.More recently, in September 2020, a proposed rule get ventolin prescription online to extend the policy to contracts was published.

If finalized, it would greatly extend the reach of the policy beyond grants and cooperative agreements to also include contracts.KFF analyses have found that:more than half of the countries in which the U.S. Provides bilateral global health assistance allow for legal get ventolin prescription online abortion in at least one case not permitted by the policy (analysis). Andhad the expanded policy been in effect during the FY 2013 – FY 2015 period, at least 1,275 foreign NGOs would have been subject to the policy (analysis).What is the Mexico City Policy?.

The Mexico City Policy is a U.S get ventolin prescription online. Government policy that – when in effect – has required foreign NGOs to certify that they will not “perform or actively promote abortion as a method of family planning” using funds from any source (including non-U.S. Funds) as a condition of receiving U.S get ventolin prescription online.

Global family planning assistance and, as of Jan. 23, 2017, get ventolin prescription online most other U.S. Global health assistance.The policy was first announced by the Reagan administration at the 2nd International Conference on Population, which was held in Mexico City, Mexico, on August 6-14, 1984 (hence its name.

See Box 1) get ventolin prescription online. Under the Trump administration, the policy has been renamed “Protecting Life in Global Health Assistance” (PLGHA). Among opponents, it is also known as the “Global Gag Rule,” because among other activities, it prohibits foreign NGOs from get ventolin prescription online using any funds (including non-U.S.

Funds) to provide information about abortion as a method of family planning and to lobby a foreign government to legalize abortion. €œ[T]he United States does not consider abortion an acceptable element of family get ventolin prescription online planning programs and will no longer contribute to those of which it is a part. €¦[T]he United States will no longer contribute to separate nongovernmental organizations which perform or actively promote abortion as a method of family planning in other nations.”When first instituted in 1984, the Mexico City Policy marked an expansion of existing legislative restrictions that already prohibited U.S.

Funding for abortion get ventolin prescription online internationally, with some exceptions (see below). Prior to the policy, foreign NGOs could use non-U.S. Funds to engage in certain voluntary abortion-related get ventolin prescription online activities as long as they maintained segregated accounts for any U.S.

Money received, but after the Mexico City Policy was in place, they were no longer permitted to do so if they wanted to receive U.S. Family planning assistance.The get ventolin prescription online Trump administration’s application of the policy to the vast majority of U.S. Bilateral global health assistance, including funding for HIV under the U.S.

President’s Emergency Plan for get ventolin prescription online AIDS Relief (PEPFAR), maternal and child health, malaria, nutrition, and other programs, marks a significant expansion of its scope, potentially encompassing $7.3 billion in FY 2020, to the extent that such funding is ultimately provided to foreign NGOs, directly or indirectly (family planning assistance accounted for approximately $600 million of that total). The Administration’s more recent extension of the policy to include any financial support (health or otherwise) provided by foreign NGOs for any purpose to other foreign NGOs that perform or actively promote abortion as a method of family planning is likely to encompass significant additional funding.When has it been in effect?. The Mexico City Policy has been in effect for 19 of the past 34 years, primarily through executive action, and has been instated, rescinded, and reinstated by presidential administrations along party lines (see Table 1).The policy was first instituted in 1984 (taking effect in 1985) by President Ronald Reagan and continued to be in effect through President George H.W.

Bush’s administration get ventolin prescription online. It was rescinded by President Bill Clinton in 1993 (although it was reinstated legislatively for one year during his second term. See below) get ventolin prescription online.

The policy was reinstated by President George W. Bush in 2001 and then rescinded by President Barack Obama in 2009 get ventolin prescription online. It is currently in effect, having been reinstated by President Trump in 2017.

YearsIn Effect? get ventolin prescription online. Presidential Administration (Party Affiliation)Executive (E) or Congressional (C) Action?. 1985-1989YesReagan (R)E1989-1993YesBush get ventolin prescription online (R)E1993-1999 Sept.NoClinton (D)E1999 Oct.-2000 Sept.Yes*Clinton (D)C2000 Oct.-2001NoClinton (D)E2001-2009YesBush (R)E2009-2017NoObama (D)E2017-presentYesTrump (R)ENOTES.

Shaded blue indicate periods when policy was in effect. * There was a temporary, one-year get ventolin prescription online legislative imposition of the policy, which included a portion of the restrictions in effect in other years and an option for the president to waive these restrictions in part. However, if the waiver option was exercised (for no more than $15 million in family planning assistance), then $12.5 million of this funding would be transferred to maternal and child health assistance.

The president get ventolin prescription online did exercise the waiver option.SOURCES. €œPolicy Statement of the United States of America at the United Nations International Conference on Population (Second Session), Mexico City, Mexico, August 6-14, 1984,” undated. Bill Clinton get ventolin prescription online Administration, “Subject.

AID Family Planning Grants/Mexico City Policy,” Memorandum for the Acting Administrator of the Agency for International Development, January 22, 1993, Clinton White House Archives, https://clintonwhitehouse6.archives.gov/1993/01/1993-01-22-aid-family-planning-grants-mexico-city-policy.html. FY 2000 Consolidated Appropriations Act, P.L get ventolin prescription online. 106-113.

George W get ventolin prescription online. Bush Administration, “Subject. Restoration of the Mexico City Policy,” Memorandum for the Administrator of the United States Agency for International Development, January 22, 2001, Bush Administration White House get ventolin prescription online Archives, https://georgewbush-whitehouse.archives.gov/news/releases/20010123-5.html.

€œSubject. Restoration of the Mexico City Policy,” Memorandum for the Administrator get ventolin prescription online of the United States Agency for International Development, March 28, 2001, Federal Register, https://www.federalregister.gov/documents/2001/03/29/01-8011/restoration-of-the-mexico-city-policy. George W.

Bush Administration, get ventolin prescription online “Subject. Assistance for Voluntary Population Planning,” Memorandum for the Secretary of State, August 29, 2003, Bush Administration White House Archives, http://georgewbush-whitehouse.archives.gov/news/releases/2003/08/20030829-3.html. Barack Obama Administration, “Mexico City Policy and Assistance for Voluntary Population Planning,” Memorandum for the Secretary of State, the Administrator of get ventolin prescription online the United States Agency for International Development, January 23, 2009, Obama White House Archives, https://obamawhitehouse.archives.gov/the-press-office/mexico-city-policy-and-assistance-voluntary-population-planning.

White House, “The Mexico City Policy,” Memorandum for the Secretary of State, the Secretary of Health and Human Services, the Administrator of the Agency for International Development, Jan. 23, 2017, https://www.whitehouse.gov/the-press-office/2017/01/23/presidential-memorandum-regarding-mexico-city-policy.How is get ventolin prescription online it instituted (and rescinded)?. The Mexico City Policy has, for the most part, been instituted or rescinded through executive branch action (typically via presidential memoranda).

While Congress has the ability to institute the policy through legislation, get ventolin prescription online this has happened only once in the past. A modified version of the policy was briefly applied by Congress during President Clinton’s last year in office as part of a broader arrangement to pay the U.S. Debt to the United get ventolin prescription online Nations.

(At that time, President Clinton was able to partially waive the policy’s restrictions.) Other attempts to institute the policy through legislation have not been enacted into law, nor have legislative attempts to overturn the policy. See Table 1.Who does the policy apply get ventolin prescription online to?. The policy, when in effect, applies to foreign NGOs as a condition for receiving U.S.

Family planning support and, now, other global health assistance, either directly (as the main – or prime – recipient of U.S. Funding) or indirectly get ventolin prescription online (as a recipient of U.S. Funding through an agreement with the prime recipient.

Referred to get ventolin prescription online as a sub-recipient). Specifically, a foreign NGO “recipient agrees that it will not, during the term of this award, perform or actively promote abortion as a method of family planning in foreign countries or provide financial support to any other foreign non-governmental organization that conducts such activities.”Foreign NGOs include:international NGOs that are based outside the U.S.,regional NGOs that are based outside the U.S., andlocal NGOs in assisted countries.U.S. NGOs, while not directly subject to the Mexico City Policy, must also agree to ensure that they do not provide funding to any foreign NGO sub-recipients unless those sub-recipients have first certified get ventolin prescription online adherence to the policy.

Specifically, a U.S. NGO “recipient (A) agrees that it will not furnish health assistance under this award to any foreign non-governmental organization that performs get ventolin prescription online or actively promotes abortion as a method of family planning in foreign countries. And (B) further agrees to require that such sub-recipients do not provide financial support to any other foreign non-governmental organization that conducts such activities.”As in the past, the current policy does not apply to funding provided by the U.S.

Government to foreign governments (national or sub-national), public international organizations, and other multilateral entities, such get ventolin prescription online as the Global Fund to Fight AIDS, Tuberculosis and Malaria and Gavi, the treatment Alliance. However, this funding is subject to the policy if it flows through a foreign NGO that has accepted the policy. See “What get ventolin prescription online is ‘financial support’?.

€ below.To what assistance does it apply?. In the past, foreign NGOs have been required to adhere to the Mexico City Policy – when it was in effect – as a condition of receiving get ventolin prescription online support through certain U.S. International funding streams.

Family planning get ventolin prescription online assistance through the U.S. Agency for International Development (USAID) and, beginning in 2003, family planning assistance through the U.S. Department of get ventolin prescription online State.

In the 2003 memorandum announcing the policy’s expansion to include the Department of State, President Bush stated that the policy did not apply to funding for global HIV/AIDS programs and that multilateral organizations that are associations of governments are not included among “foreign NGOs.”The current policy, reinstated in 2017, applies to the vast majority of U.S. Bilateral global health assistance furnished by all get ventolin prescription online agencies and departments. “Assistance” includes “the provision of funds, commodities, equipment, or other in-kind global health assistance.” Specifically, the expanded policy applies to nearly all bilateral global health assistance, including.

family planning and reproductive healthfor the first time:maternal and child get ventolin prescription online health (including household-level water, sanitation, and hygiene (WASH))nutritionHIV under PEPFARtuberculosismalaria under the President’s Malaria Initiative (PMI)neglected tropical diseasesglobal health securitycertain types of research activitiesThe policy applies to the assistance described above that is appropriated directly to three agencies and departments. USAID. The Department of State, get ventolin prescription online including the Office of the Global AIDS Coordinator, which oversees and coordinates U.S.

Global HIV funding under PEPFAR. And for the first time, get ventolin prescription online the Department of Defense (DoD). When such funding is transferred to another agency, including the Centers for Disease Control (CDC) and the National Institutes of Health (NIH), it remains subject to the policy, to the extent that such funding is ultimately provided to foreign NGOs, directly or indirectly.The policy applies to three types of funding agreements for such assistance.

Grants. Cooperative agreements. And, for the first time, contracts, pending necessary rule-making that would be needed to do so (a proposed rule to accomplish this was published in September 2020).The policy does not apply to U.S.

Assistance for. Water supply and sanitation activities, which is usually focused on infrastructure and systems. Humanitarian assistance, including activities related to migration and refugee assistance activities as well as disaster and humanitarian relief activities.

The American Schools and Hospitals Abroad (ASHA) program. And Food for Peace (FFP). However, this funding is subject to the policy if it flows through a foreign NGO that has accepted the policy.

See “What is ‘financial support’?. € below.What activities are prohibited?. The policy prohibits foreign NGOs that receive U.S.

Family planning assistance and, now, most other U.S. Bilateral global health assistance from using funds from any source (including non-U.S. Funds) to “perform or actively promote abortion as a method of family planning.” In addition to providing abortions with non-U.S.

Funds, restricted activities also include the following:providing advice and information about and offering referral for abortion – where legal – as part of the full range of family planning options,promoting changes in a country’s laws or policies related to abortion as a method of family planning (i.e., engaging in lobbying), andconducting public information campaigns about abortion as a method of family planning.The prohibition of these activities are why the policy has been referred to by its critics as the “Global Gag Rule.”Additionally, for the first time, the policy prohibits foreign NGOs from providing any financial support with any source of funds (including non-U.S. Funding) and for any purpose to other foreign NGOs that perform or actively promote abortion as a method of family planning. See “What is “financial support?.

€ below.The policy, however, does not prohibit foreign NGOs from:providing advice and information about, performing, or offering referral for abortion in cases where the pregnancy has either posed a risk to the life of the mother or resulted from incest or rape. Andresponding to a question about where a safe, legal abortion may be obtained when a woman who is already pregnant clearly states that she has already decided to have a legal abortion (passively providing information, versus actively providing medically-appropriate information).In addition, the expanded policy does not apply to healthcare providers who have an affirmative duty required under local law to provide counseling about and referrals for abortion as a method of family planning.Does it restrict direct U.S. Funding for abortion overseas?.

U.S. Funding for abortion is already restricted under several provisions of the law. Specifically, before the Mexico City Policy was first announced in 1984, U.S.

Law already prohibited the use of U.S. Aid:to pay for the performance of abortion as a method of family planning or to motivate or coerce any person to practice abortion (the Helms Amendment, 1973, to the Foreign Assistance Act);for biomedical research related to methods of or the performance of abortion as a means of family planning (the Biden Amendment, 1981, to the Foreign Assistance Act). Andto lobby for or against abortion (the Siljander Amendment, first included in annual appropriations in 1981 and included each year thereafter).Then, shortly after the policy was announced in 1984, the Kemp-Kasten Amendment was passed in 1985, prohibiting the use of U.S.

Aid to fund any organization or program, as determined by the president, that supports or participates in the management of a program of coercive abortion or involuntary sterilization (it is now included in annual appropriations).Before the Mexico City Policy, U.S. Aid recipients could use non-U.S. Funds to engage in certain abortion-related activities but were required to maintain segregated accounts for U.S.

Assistance. The Mexico City Policy reversed this practice. No longer were foreign NGOs allowed to use non-U.S.

Funds, maintained in segregated accounts, for voluntary abortion-related activities if they wished to continue to receive or be able to receive U.S. Family planning funds.Does the policy prohibit post-abortion care?. The Mexico City Policy does not restrict the provision of post-abortion care, which is a supported activity of U.S.

Family planning assistance. Whether or not the Mexico City Policy is in effect, recipients of U.S. Family planning assistance are allowed to use U.S.

And non-U.S. Funding to support post-abortion care, no matter the circumstances of the abortion (whether it was legal or illegal).What has been the impact of the policy?. Several studies have looked at the impact of the policy.

A 2011 quantitative analysis by Bendavid, et. Al, found a strong association between the Mexico City Policy and abortion rates in sub-Saharan Africa. This study was recently updated to include several more years of data, again identifying a strong association.

Specifically, the updated study found that during periods when the policy was in place, abortion rates rose by 40% in countries with high exposure to the Mexico City Policy compared to those with low exposure, while the use of modern contraceptives declined by 14% and pregnancies increased by 12% in high exposure compared to low exposure countries. In other words, it found patterns that “strengthen the case for the role played by the policy” in “a substantial increase in abortions across sub-Saharan Africa among women affected by the U.S. Mexico City Policy … [and] a corresponding decline in the use of modern contraception and increase in pregnancies,” likely because foreign NGOs that declined U.S.

Funding as a result of the Mexico City Policy – often key providers of women’s health services in these areas – had fewer resources to support family planning services, particularly contraceptives. Increased access to and use of contraception have been shown to be key to preventing unintended pregnancies and thereby reducing abortion, including unsafe abortion. The study also found patterns that “suggest that the effects of the policy are reversible” when the policy is not in place.Additionally, there has been anecdotal evidence and qualitative data on the impact of the policy, when it has been in force in the past, on the work of organizations that have chosen not to agree to the policy and, therefore, forgo U.S.

Funding that had previously supported their activities. For example, they have reported that they have fewer resources to support family planning and reproductive health services, including family planning counseling, contraceptive commodities, condoms, and reproductive cancer screenings.While it is likely too early to assess the full effects of the current policy on NGOs and the individuals they serve, as the policy is applied on a rolling basis as new funding agreements or modifications to existing agreements are made, some early data are available. Several early qualitative and quantitative studies have been released, and at least one long-term, quantitative assessment is underway.

Additionally, an official assessment by the U.S. Department of State on implementation during the first six months of the policy has been released (see below). This review acknowledged that it took “place early in the policy’s implementation, when affected U.S.

Government departments and agencies have added a significant portion of the funding affected by the policy to grants and cooperative agreements only recently [i.e., after the period the review examined]. A follow-on analysis would allow an opportunity to address one of the primary concerns presented in feedback from third-party stakeholder organizations, namely that six months is insufficient time to gauge the impacts of” the policy.Nonetheless, it is already clear that the reinstated and expanded version of the policy applies to a much greater amount of U.S. Global health assistance, and greater number of foreign NGOs, across many program areas.

KFF has found that more than half (37) of the 64 countries that received U.S. Bilateral global health assistance in FY 2016 allow for legal abortion in at least one case not permitted by the policy and that had the expanded Mexico City Policy been in effect during the FY 2013 – FY 2015 period, at least 1,275 foreign NGOs would have been subject to the policy. In addition, at least 469 U.S.

NGOs that received U.S. Global health assistance during this period would have been required to ensure that their foreign NGO sub-recipients were in compliance. Additional foreign NGOs are likely to be impacted by the policy due to the revised interpretation of “financial support” announced in March 2019 and implemented beginning June 2019.

See “What is ‘financial support’?. € below.A report released in March 2020 by the U.S. Government Accountability Office (GAO) provided new information on the number of projects (awards) and NGOs affected.

It found that from May 2017 through FY 2018:the policy had been applied to over 1,300 global health projects, with the vast majority of these through USAID and CDC, andNGOs declined to accept the policy in 54 instances, totaling $153 million in declined funding – specifically, seven prime awards amounting to $102 million and 47 sub-awards amounting to $51 million (more than two-thirds of sub-awards were intended for Africa) – across USAID and CDC. The Department of State and DoD did not identify any instances where NGOs declined to accept the policy conditions.What have the U.S. Government’s reviews of the policy found?.

The U.S. Government has published two reviews of the policy to date, with the first examining the initial six months of the policy released in February 2018 and the second examining the first 18 months of the policy released in August 2020.First ReviewIn February 2018, the Department of State announced the findings of an initial six-month review of implementation of the policy through the end of FY 2017 (September 2017). The report directed agencies to provide greater support for improving understanding of implementation among affected organizations and provided guidance to clarify terms included in standard provisions of grants and cooperative agreements.

In the six-month review report, the Department of State report identified a number of “actions” for implementing agencies, such as a need for:more central and field-based training and implementation tools,a clearer explanation of termination of awards for NGOs found to be in violation of the policy, anda clarification of “financial support,” which was not defined in the standard provisions (see “What is financial support?. € below).The six month review also identified the number of affected agreements with prime implementing partners and the number of those that have accepted the Mexico City Policy as part of their agreements through September 2017 (see Table 2). U.S.

Agency or DepartmentPolicy Implementation DateOverall # of Grants and Cooperative Agreements with Global Health Assistance FundingOf Overall #:(From the Policy Implementation Date through 9/30/2017)# That Received New Funding and Accepted Policy# That Received New Funding and Declined to Accept Policy^# That Had Not Received New Funding YetUSAIDMay 15, 20175804193158State*May 15, 2017142108034HHS+May 31, 20174991600339DoDMay 15, 20177742134TOTAL12987294565NOTES. * reflects PEPFAR funding implemented through the Department of State. Other departments and agencies implement the majority of PEPFAR funding.

+ At HHS agencies, only certain assistance funding transferred from USAID, State, and DoD are subject to the policy. ^ As of September 30, 2017, USAID reported it was aware of three centrally funded prime partners, and 12 sub-awardee implementing partners, that declined to agree to the Protecting Life in Global Health Assistance (PLGHA) terms in their awards. DoD reported that one DoD partner, a U.S.

NGO, declined to agree in one country but accepted the PLGHA standard provision in other countries. And HHS reported that no HHS partners declined to agree.SOURCES. KFF analysis of data from Department of State, “Protecting Life in Global Health Assistance Six-Month Review,” report, Feb.

6, 2018, https://www.state.gov/protecting-life-in-global-health-assistance-six-month-review/.Second ReviewOn August 17, 2020, the Department of State released its second review of the policy, updating its initial six-month review (as an action item in the six-month review report, the department stated it would “conduct a further review of implementation of the policy by December 15, 2018, when more extensive experience will enable a more thorough examination of the benefits and challenges”). The long-anticipated review, which examines the period from May 2017 through September 2018, found:the awards declined spanned a variety of program areas, including family planning and reproductive health (FP/RH), HIV and AIDS (HIV/AIDS), maternal and child health (MCH), tuberculosis (TB), and nutrition, in addition to cross-cutting awards;the awards declined spanned geographic areas but many were for activities in sub-Saharan Africa;agencies and departments made efforts to transition projects to another implementer in order to minimize disruption. Butnevertheless, among USAID awards involving health service delivery where prime and sub-award recipients declined to accept the policy, gaps or disruptions in service delivery were sometimes reported.The second review also identified the number of affected agreements with prime implementing partners and the number of those that have accepted the Mexico City Policy as part of their agreements through September 2018 (see Table 3).

U.S. Agency or DepartmentPolicy Implementation Date# of Grants and Cooperative Agreements with Global Health Assistance Funding# of Prime Awardees That Declined to Accept Policy^USAIDMay 15, 20174866State*May 15, 20173350HHS+May 31, 20174661DoDMay 15, 2017531TOTAL13408NOTES. * reflects PEPFAR funding implemented through the Department of State.

Other departments and agencies implement the majority of PEPFAR funding. + At HHS agencies, only certain assistance funding transferred from USAID, State, and DoD are subject to the policy. ^ As of September 30, 2018, USAID reported it was aware of six centrally funded prime partners, and 47 sub-awardee implementing partners, that declined to agree to the Protecting Life in Global Health Assistance (PLGHA) terms in their awards.

DoD reported that one DoD partner, a U.S. NGO, declined to agree in one country but accepted the PLGHA standard provision in other countries. And HHS reported that one HHS partner declined to agree.SOURCES.

KFF analysis of data from Department of State, “Review of the Implementation of the Protecting Life in Global Health Assistance Policy ,” report, Aug. 17, 2020, https://www.state.gov/wp-content/uploads/2020/08/PLGHA-2019-Review-Final-8.17.2020-508.pdf, and Department of State, “Protecting Life in Global Health Assistance Six-Month Review,” report, Feb. 6, 2018, https://www.state.gov/protecting-life-in-global-health-assistance-six-month-review/.Additionally, the review reports that 47 sub-awardees, all under USAID awards, declined to accept the policy.

It is important to note that the review also states that information on sub-awards is not systematically collected by departments and agencies and that DoD was not able to collect information on sub-awards.What is “financial support”?. In February 2018, in the initial six-month review issued when Secretary of State Tillerson led the department, the Department of State report included an “action” statement to clarify the definition of “financial support” as used in the standard provisions for grants and cooperative agreements. At issue was whether it applied more narrowly to certain funding provided by foreign NGOs (i.e., funding other than U.S.

Global health funding) to other foreign NGOs specifically for the purpose of performing or actively promoting abortion as a method of family planning or if it applied more broadly to certain funding provided by foreign NGOs to other foreign NGOs for any purpose, if that foreign NGO happened to perform or actively promote abortion as a method of family planning. The State Department clarified that it was the more narrow interpretation.However, on March 26, 2019, Secretary of State Pompeo reversed this interpretation, announcing further “refinements” to the policy to clarify that it applied to the broader definition of financial support. Specifically, under the policy, U.S.-supported foreign NGOs agree to not provide any financial support (global health-related as well as other support), no matter the source of funds, to any other foreign NGO that performs or actively promotes abortion as a method of family planning.

In June 2019, USAID provided additional information to reflect this broader interpretation of the standard provisions.This marks the first time the policy has been applied this broadly, as it can now affect funding provided by other donors (such as other governments and foundations) and non-global health funding provided by the U.S. Government for a wide range of purposes if this funding is first provided to foreign NGOs who have accepted the policy (as recipients of U.S. Global health assistance) that then in turn provide that donor or U.S.

Non global health funding for any purpose to foreign NGOs that perform or actively promote abortion as a method of family planning. For example, under the prior interpretation, a foreign NGO recipient of U.S. Global health funding could not provide any non-U.S.

Funding to another foreign NGO to perform or actively promote abortion as a method of family planning but could provide funding for other activities, such as education, even if the foreign NGO carried out prohibited activities. Under the broader interpretation, a foreign NGO could not provide any non-U.S. Funding for any activity to a foreign NGO that carried out prohibited activities.

Similarly, while under the prior interpretation a foreign NGO recipient of U.S. Global health funding could provide other U.S. Funding (such as humanitarian assistance) to another foreign NGO for non-prohibited activities, even if the foreign NGO carried out prohibited activities, now under the broader interpretation, it could not do so.What are the next steps in implementing the expanded policy?.

The policy went into effect in May 2017 (see Table 2), although it is applied on a rolling basis, as new funding agreements and modifications to existing agreements occur. While it applies to all grants and cooperative agreements, the Trump administration has indicated that it intends the policy to apply to contracts, which would require a rule-making process (it began this process by publishing a proposed rule in September 2020)..

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It may sound like Cialis generic best price fodder for a supervillain origin story, but doctors experimenting on themselves in the name of science isn't as rare as you might think ventolin bodybuilding. And whether you view these forays as foolhardy or heroic, many have actually affirmed the science behind them. In a study of 465 cases of medical self-experimentation ventolin bodybuilding over the past 200 years, 89% led to results which supported the experimenter’s hypothesis.

Even when the results were negative, some cases could still be considered beneficial due to their impact on future research. Self-experimentation is controversial subject, with valid considerations both for and against the idea. But there’s no denying that ventolin bodybuilding these experiments have led to novel discoveries in a number of areas.

Here are five physicians who put themselves under the scalpel (sometimes literally) for the sake of scientific advancement. William Stark(Credit. Wellcome Images/CC-by-4.0/Wikimedia ventolin bodybuilding Commons)In 1769, William Stark embarked on a series of self-experiments related to diet and nutrition.

He started by going for 31 days consuming almost nothing but bread and water — and a little sugar. Then he gradually added other foods, one at a time. These included goose, beef, veal, and olive ventolin bodybuilding oil.

What Stark didn’t include, however, was citrus fruit or vegetables. His gums started to bleed and his symptoms mimicked those of British sailors suffering from scurvy. Severely malnourished, ventolin bodybuilding in less than a year he died of scurvy at only 29 years old.

Although Stark didn’t discover scurvy, his research led to realization that the disease was strongly impacted by what we now call vitamin C deficiency. And his meticulous record-keeping would help substantiate the theory that restrictive diets lacking variety were not beneficial to human health. However, ascorbic acid, more commonly known as vitamin C, would ventolin bodybuilding not be discovered by biochemist Albert Szent-Györgyi until the 1930s.Werner Forssmann(Credit.

Public Domain/Wikimedia Commons)A cardiac catheterization — where a thin, hollow tube called a catheter is inserted into a blood vessel leading to the heart — is a procedure used to diagnose and treat a number of cardiovascular conditions. Essentially, it shows doctors how well a patient's heart is working. With over a million done ventolin bodybuilding each year in the United States, it’s one of the most frequently performed cardiac procedures.German physician Werner Forssmann is the father of this particular medical advancement.

In 1929, Forssmann made an incision into the inside of his elbow and then inserted a roughly 25 inch urinary catheter into his vein. Guided by a real-time imaging technique called a fluoroscope, he advanced it to his heart’s right auricle, or atrium, and then had X-rays taken to confirm the position. Forssmann next tried the procedure on a terminally ill woman, and found ventolin bodybuilding he was able to effectively deliver medication directly to her heart.

He continued to experiment further, using rabbits, dogs, and himself — totaling up to nine additional catheterizations. The results of his work led other physicians to use the femoral vein, deep within the thigh, to reach the inferior vena cava, which carries blood from the legs, feet and abdomen to the heart. Forssmann is a Nobel Prize winner and considered a pioneer in interventional cardiology.Barry ventolin bodybuilding Marshall(Credit.

WikiEdtingProfile2021/CC-by-3.0/Wikimedia Commons) For years, conventional wisdom was that excessive stomach acid was the culprit behind ulcers, painful sores that develop on the lining of the stomach or small intestine. Barry Marshall, an Australian physician, disagreed — he believed that ventolin bodybuilding ulcers were actually caused by the bacterium Helicobacter pylori, which commonly lives in the stomach lining. Marshall's interest in the subject was spurred by pathobiologist Robin Warren, who had observed the bacteria in a biopsy from a patient’s stomach lining in 1979.

After teaming up, the pair studied biopsies from 100 patients and found that almost every one with ulcers or gastritis (any condition where the stomach lining is inflamed) also had H. Pylori. But after years of trying to persuade skeptics, and with no suitable animal models to work with, Marshall was driven to dig deeper.

He took bacteria samples from a sick patient and drank it in a “brew.” Afterwards, Marshall became sick with bloating, decreased appetite, and eventually vomiting. An endoscopy confirmed he did indeed have gastritis, and antibiotic treatment proved an effective cure. Marshall's experiment confirmed the connection between H.

Pylori and ulcers. As a result, antibiotics are now the standard treatment. In 2005, Marshall and Warren won the Nobel Prize in physiology for their groundbreaking discovery.Read more about Marshall in our 2010 interview.

The Doctor Who Drank Infectious Broth, Gave Himself an Ulcer, and Solved a Medical MysteryEvan O’Neill KaneSurgeon Evan O'Neill Kane was no stranger to appendectomies, having performed over 4,000 himself. But after nearly 40 years in the operating room, Kane wanted to prove that, in certain cases, local anesthetic could be used as an alternative to the riskier general anesthesia. To prove his theory, in 1921 he decided to make himself a test case.

When his appendix became infected, he was scheduled to have the organ removed by another surgeon. But right before his appendectomy began, Kane announced that he would be doing the surgery himself. First, Kane propped himself up on pillows, so he could better see his abdomen.

Then he injected the area with a local anesthetic containing cocaine and adrenaline before cutting through the tissue and locating and removing his infected appendix. Kane was not new to self-surgery. Two years prior to his appendectomy, he amputated his own finger due to .

Years later, he successfully operated on his hernia — at age 70 — and was back in the operating room only 36 hours later. Kane’s bold decision led to a greater understanding about the use of local anesthetics, and how to avoid general anesthesia in patients for whom it posed a danger.Alexander Bogdanov(Credit. Public Domain/Wikimedia Commons) As an influential member of the Bolsheviks, physician Alexander Bogdanov competed with Vladimir Lenin to lead the leftist revolutionary movement, offering Russians a more moderate alternative.

It didn’t work out, but Bogdanaov, a true polymath, had other skills and talents to explore. In addition to being a physician, he was also an economist, philosopher, poet, science fiction writer, teacher, and founder of the first institution dedicated to blood transfusion. His interest in transfusions stemmed from his belief that it could extend human life.

During the 1920’s, Bogdanov gave himself multiple transfusions. Unfortunately, one of his transfusions involved the use of a student’s blood, who was sick with malaria and tuberculosis. Bogdanov died, but the student survived his illness.

Building on his work, his successors made advances that established Russia as a leader in developing a central national blood transfusion system..

It may sound like fodder for a supervillain origin story, but doctors experimenting on themselves in the name of science isn't as rare get ventolin prescription online as you might think. And whether you view these forays as foolhardy or heroic, many have actually affirmed the science behind them. In a study of 465 cases of medical self-experimentation over the past 200 years, 89% led to results which supported the experimenter’s hypothesis get ventolin prescription online. Even when the results were negative, some cases could still be considered beneficial due to their impact on future research.

Self-experimentation is controversial subject, with valid considerations both for and against the idea. But there’s no get ventolin prescription online denying that these experiments have led to novel discoveries in a number of areas. Here are five physicians who put themselves under the scalpel (sometimes literally) for the sake of scientific advancement. William Stark(Credit.

Wellcome Images/CC-by-4.0/Wikimedia Commons)In 1769, William Stark embarked on a series get ventolin prescription online of self-experiments related to diet and nutrition. He started by going for 31 days consuming almost nothing but bread and water — and a little sugar. Then he gradually added other foods, one at a time. These included get ventolin prescription online goose, beef, veal, and olive oil.

What Stark didn’t include, however, was citrus fruit or vegetables. His gums started to bleed and his symptoms mimicked those of British sailors suffering from scurvy. Severely malnourished, in less than a get ventolin prescription online year he died of scurvy at only 29 years old. Although Stark didn’t discover scurvy, his research led to realization that the disease was strongly impacted by what we now call vitamin C deficiency.

And his meticulous record-keeping would help substantiate the theory that restrictive diets lacking variety were not beneficial to human health. However, ascorbic get ventolin prescription online acid, more commonly known as vitamin C, would not be discovered by biochemist Albert Szent-Györgyi until the 1930s.Werner Forssmann(Credit. Public Domain/Wikimedia Commons)A cardiac catheterization — where a thin, hollow tube called a catheter is inserted into a blood vessel leading to the heart — is a procedure used to diagnose and treat a number of cardiovascular conditions. Essentially, it shows doctors how well a patient's heart is working.

With over a million done each year in the United States, it’s one of the most frequently get ventolin prescription online performed cardiac procedures.German physician Werner Forssmann is the father of this particular medical advancement. In 1929, Forssmann made an incision into the inside of his elbow and then inserted a roughly 25 inch urinary catheter into his vein. Guided by a real-time imaging technique called a fluoroscope, he advanced it to his heart’s right auricle, or atrium, and then had X-rays taken to confirm the position. Forssmann next tried the procedure on a terminally ill woman, and get ventolin prescription online found he was able to effectively deliver medication directly to her heart.

He continued to experiment further, using rabbits, dogs, and himself — totaling up to nine additional catheterizations. The results of his work led other physicians to use the femoral vein, deep within the thigh, to reach the inferior vena cava, which carries blood from the legs, feet and abdomen to the heart. Forssmann is a Nobel Prize winner get ventolin prescription online and considered a pioneer in interventional cardiology.Barry Marshall(Credit. WikiEdtingProfile2021/CC-by-3.0/Wikimedia Commons) For years, conventional wisdom was that excessive stomach acid was the culprit behind ulcers, painful sores that develop on the lining of the stomach or small intestine.

Barry Marshall, an Australian physician, disagreed — he believed that ulcers get ventolin prescription online were actually caused by the bacterium Helicobacter pylori, which commonly lives in the stomach lining. Marshall's interest in the subject was spurred by pathobiologist Robin Warren, who had observed the bacteria in a biopsy from a patient’s stomach lining in 1979. After teaming up, the pair studied biopsies from 100 patients and found that almost every one with ulcers or gastritis (any condition where the stomach lining is inflamed) also had H. Pylori.

But after years of trying to persuade skeptics, and with no suitable animal models to work with, Marshall was driven to dig deeper. He took bacteria samples from a sick patient and drank it in a “brew.” Afterwards, Marshall became sick with bloating, decreased appetite, and eventually vomiting. An endoscopy confirmed he did indeed have gastritis, and antibiotic treatment proved an effective cure. Marshall's experiment confirmed the connection between H.

Pylori and ulcers. As a result, antibiotics are now the standard treatment. In 2005, Marshall and Warren won the Nobel Prize in physiology for their groundbreaking discovery.Read more about Marshall in our 2010 interview. The Doctor Who Drank Infectious Broth, Gave Himself an Ulcer, and Solved a Medical MysteryEvan O’Neill KaneSurgeon Evan O'Neill Kane was no stranger to appendectomies, having performed over 4,000 himself.

But after nearly 40 years in the operating room, Kane wanted to prove that, in certain cases, local anesthetic could be used as an alternative to the riskier general anesthesia. To prove his theory, in 1921 he decided to make himself a test case. When his appendix became infected, he was scheduled to have the organ removed by another surgeon. But right before his appendectomy began, Kane announced that he would be doing the surgery himself.

First, Kane propped himself up on pillows, so he could better see his abdomen. Then he injected the area with a local anesthetic containing cocaine and adrenaline before cutting through the tissue and locating and removing his infected appendix. Kane was not new to self-surgery. Two years prior to his appendectomy, he amputated his own finger due to .

Years later, he successfully operated on his hernia — at age 70 — and was back in the operating room only 36 hours later. Kane’s bold decision led to a greater understanding about the use of local anesthetics, and how to avoid general anesthesia in patients for whom it posed a danger.Alexander Bogdanov(Credit. Public Domain/Wikimedia Commons) As an influential member of the Bolsheviks, physician Alexander Bogdanov competed with Vladimir Lenin to lead the leftist revolutionary movement, offering Russians a more moderate alternative. It didn’t work out, but Bogdanaov, a true polymath, had other skills and talents to explore.

In addition to being a physician, he was also an economist, philosopher, poet, science fiction writer, teacher, and founder of the first institution dedicated to blood transfusion. His interest in transfusions stemmed from his belief that it could extend human life. During the 1920’s, Bogdanov gave himself multiple transfusions. Unfortunately, one of his transfusions involved the use of a student’s blood, who was sick with malaria and tuberculosis.

Bogdanov died, but the student survived his illness. Building on his work, his successors made advances that established Russia as a leader in developing a central national blood transfusion system..

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